Poster
The immune response to HIV
Nina Bhardwaj, Florian Hladik and Susan Moir
Nature Reviews ImmunologyVolume 15, No 7 July 2015
Article body
A global research effort over the past three decades has discovered more about HIV than perhaps any other pathogen. Immunologists continue to be intrigued by the capacity of HIV to effectively knock out an essential component of the adaptive immune system — CD4+ T helper cells. Based on a clearer understanding of HIV infection and the response to it, the field has now entered an era of renewed optimism for the development of a successful vaccine.
This Poster summarizes how HIV establishes infection at mucosal surfaces, the ensuing immune response to the virus involving dendritic cells, B cells and T cells, and how HIV subverts this response to establish a chronic infection.
The Poster is freely available thanks to support from STEMCELL Technologies.
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